We think of scientists as sober, precise thinkers, but they can be wildly off the mark. Consider cold fusion, N-rays, or polywater--three "discoveries" that turned out to be complete nonsense. But serious scientists somehow convinced themselves that they were real.
In The Undergrowth of Science, Walter Gratzer recounts the blind alleys that honest, dedicated researchers have wandered down--and had to be dragged out of by more cool-headed colleagues...