The Regulation of Expression of Terminal Deoxynucleotidyl Transferase in an Inducible Murine Pre-B Cell Line

by Randy Horwitz

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Abstract:

The purpose of this study was to understand the control of synthesis of Tdt at a molecular level, using a murine pre B-cell line inducible for the enzyme. FLEl-4, an Abelson virus transformed fetal liver cell line, when treated with dibutyryl cAMP and caffeine (or other phosphodiesterase inhibitors), shows a three- to tenfold induction of Tdt, as measured by immunoprecipitation of pulse labelled enzyme, activity assays, and steady-state...

Format:Paperback

Language:English

ISBN:0530018586

ISBN13:9780530018584

Release Date:December 2019

Publisher:Dissertation Discovery Company

Length:226 Pages

Weight:1.18 lbs.

Dimensions:0.5" x 8.5" x 11.0"

Related Subjects

Medical Medical Books Science Science & Math Science & Scientists Science & Technology

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The Regulation of Expression of Terminal Deoxynucleotidyl Transferase in an Inducible Murine Pre-B Cell Line

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