1. Introduction 1.1 Ribosomal antibiotics: function, activity and selectivity 1.2 Pleuromutilins: a class of PTC ribosomal antibiotics for clinical use 1.3 Structural basis for cross-resistance between ribosomal PTC antibiotics 1.4 Oligonucleotides as ribosomal inhibitors and as tools for structural and functional study 1.5 Minimal ribosomal components with PTC structure and function 2. Methods 2.1...