Volume 40 of "Progress in Drug Research" contains six reviews and the various indexes which facilitate its use and establish the connec- tion with the previous volumes. The articles in this volume deal with phosphodiesterase inhibitors and their therapeutic potential in asthma; peptide receptor ligand drugs; aldose reductase inhibitors; the design and discovery of new drugs by stepping-down and stepping-up approaches; new synthetic ligands for L-type...