Phosphodiesterases as Drug Targets
(Book #204 in the Handbook of experimental pharmacology Series)
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Book Overview
Phosphodiesterase inhibitors: History of pharmacology; PDE inhibitors: factors that influence potency, selectivity and action; A fission yeast-based platform for phosphodiesterase inhibitor high throughput screening and analyses of phosphodiesterase activity; The pharmacokinetics of PDE inhibitors and the impact of this on their efficacy and the therapeutic window; Structural insight into the substrate specificity of phosphodiesterases; The GAF-tandem...
Format:Paperback
Language:English
ISBN:3642269451
ISBN13:9783642269455
Release Date:November 2013
Publisher:Springer
Length:522 Pages
Weight:1.65 lbs.
Dimensions:1.1" x 6.1" x 9.2"
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