The Canalis Sinuosus (CS) is a neurovascular canal, through which the Anterior Superior Alveolar Nerve (ASAN) passes and then curves medially in path between the nasal cavity and the maxillary sinus, reaching the premaxilla in the canine to incisor region. The purpose of this article is to report two cases with the presence of Canalis Sinuosus, in order to alert and guide professionals and discuss the morphology of this anatomical variation avoiding...