Mesenchymal Stromal Cells: Biology and Clinical Applications

MSCs in regenerative medicine: A perspective.- MSCs: Changing hypotheses, paradigms, and controversies on mechanisms of action in repairing tissues.- MSCs: the need to rethink.- Characterization of MSCs: From early studies to the present.- MSCs as therapeutics.- MSC niche for hematopoiesis.- Immunomodulatory properties of MSCs.- MSCs and the innate immune system: A balancing act.- MSCs: paracrine effects.- Cross-talk between MSCs and their environments.- Human MSCs from bone marrow, umbilical cord blood and adipose tissue: all the same?.- MSCs in solid tumors and hematological malignancies: from basic biology to therapeutic potential.- MSC studies in large animal Models.- Defining the potential of MSCs with a prenatal large animal Model .- Bench-to-bedside development of MSC based therapies: A multidisciplinary approach.- GMP production of MSCs.- MSCs: The USA regulatory perspective.- MSCs: Clinical applications and European regulatory aspects.- Stem cell treatments around the world: boon or bane?.- Safety issues in MSC therapy.- In Vivo imaging of MSCs.- National Heart, Lung, and Blood Institute support of cellular therapies regenerative medicine.- MSC therapy of inborn errors.- MSCs for enhancement of hematopoietic progenitor cell engraftment and poor graft function.- MSCs for graft-versus-host disease.- MSCs in paediatric hematopoietic stem cell transplantation.- MSCs for ex vivo expansion of umbilical cord blood cells.- MSCs for autoimmune disorders.- MSCs for induction of solid organ allograft acceptance.- MSCs for gastrointestinal disorders.- MSCs for cardiac repair.- MSCs for acute lung injury.- MSCs for diabetes.- MSCs for renal repair.- MSCs for the treatment of stroke, spinal cord injury, and traumatic brain injury: From bench work to clinical trials.- MSCs in reconstructive surgery.- MSCs in orthopedic surgery.- Adipose tissue derived MSCs: Moving to the clinic.