By the end of the fifteenth century, Cassandra Fedele (1465-1558), a learned middle-class woman of Venice, was arguably the most famous woman writer and scholar in Europe. A cultural icon in her own time, she regularly corresponded with the king of France, lords of Milan and Naples, the Borgia pope Alexander VI, and even maintained a ten-year epistolary exchange with Queen Isabella and King Ferdinand of Spain that resulted in an invitation for her...