Queen Isabel of Castile is perhaps best known for her patronage of Christopher Columbus and for the religious zeal that led to the Spanish Inquisition, the waging of holy war, and the expulsion of Jews and Muslims across the Iberian peninsula. In this sweeping biography, newly revised and annotated to coincide with the five-hundredth anniversary of Isabel's death, Peggy K. Liss draws upon a rich array of sources to untangle the facts, legends,...