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Hardcover Intramembrane-Cleaving Proteases (I-CLiPs) Book

ISBN: 1402063105

ISBN13: 9781402063107

Intramembrane-Cleaving Proteases (I-CLiPs)

In recent years a growing number of proteases have been identified that catalyse peptide bond hydrolysis in the plane of the cellular membrane. These so-called 'intramembrane-cleaving proteases' (I-CLiPs) are involved in a diverse range of cellular processes, including cell regulation, signalling, quorum sensing, protein processing, lipid metabolism and the unfolded protein response. Some I-CLiPs play critical roles in diseases such as Alzheimer's...

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Format: Hardcover

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