How to be a Laboratory Biosafety Officer. The Lab Biosafety Officer position is responsible for ensuring laboratory safety and security against all hazards including biological, chemical and physical hazards. This includes containment of infectious organisms, knowledge of Biosafety Containment Levels (BSL), proper use of Personal Protective Equipment (PPE), Biosafety Cabinets (BSC), isolation precautions and infection control, knowledge of disinfection,...