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Paperback G-Quadruplex DNA: Methods and Protocols Book

ISBN: 1493956396

ISBN13: 9781493956395

G-Quadruplex DNA: Methods and Protocols

(Book #608 in the Methods in Molecular Biology Series)

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Book Overview

Recent work has revealed that stabilizing G-quadruplexes in telomeric DNA inhibits telomerase activity, providing impetus for the development of G-quartet-interacting drugs, while G-quartet-containing oligonucleotides have been recognized as a potent class of aptamers effective against STAT3 and other transcription factors implicated in oncogenesis, proving these guanine-quartets to be a vital and rich area for future study. In "G-Quadruplex DNA:...

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