Jim Kildare, MD (Richard Chamberlain) starts his third year at Blair General Hospital newly promoted to the position of Chief Resident by mentor and Chief of Staff Dr. Leonard Gillespie (Raymond Massey). Dr. Kildare now adds the care, training and protection of Blair General's staff of interns to his duties in addition to grappling with challenges as far-reaching and prescient as steroid-psychosis, low calorie weight gain, and the tragic fall-out...