Differential Wnt/Wingless Dysregulation in Intestinal cancers

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Wnt/Wingless pathway dysregulation leading to -catenin stabilization, a central downstream component is widely associated with Intestinal carcinogenesis. Majority of tumors arise as a result of mutational inactivation of tumor suppressor gene Adenomatous Polyposis Coli (APC). This study identifies alternative mechanism of -catenin stabilization in tumors that lack APC mutations. Tumor known to lack APC mutations, small bowel cancers and early age...

Format:Paperback

Language:English

ISBN:363966759X

ISBN13:9783639667592

Release Date:December 2014

Publisher:Scholars' Press

Length:156 Pages

Weight:0.52 lbs.

Dimensions:0.4" x 6.0" x 9.0"

Related Subjects

Science Science & Math Science & Scientists Science & Technology

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Differential Wnt/Wingless Dysregulation in Intestinal cancers

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