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Paperback Data-Driven Modeling of Molecular Interactions at the Trans-Golgi Network of Mammalian Cells Book

ISBN: 3832540237

ISBN13: 9783832540234

Data-Driven Modeling of Molecular Interactions at the Trans-Golgi Network of Mammalian Cells

In this thesis simulation models have been developed and validated to investigate the protein-lipid interaction mechanisms at the trans-Golgi network (TGN) of mammalian cells. In two systems biological studies, ordinary differential equation models were used to examine the interactions between the lipids involved in the sphingomyelin synthase 1 reaction at the TGN and the proteins involved in the regulation of non-vesicular Endoplasmic reticulum to...

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