P-450 has in common with our nation that it can call Phila- delphia its hometown. Yet there are differences, too. The U. S. A. was born and named in this city. P-450 was first recog- nized here -- an odd CO-combining pigment without family or func- tion. Japanese workers identified it as an unusual member of the cytochrome family. Finally, in Philadelphia, its biological func- tion was established and its growth to a global power initiated. Since...