Gastroesophageal reflux disease (GERD) is one of the most common health conditions affecting Americans. A study of an employed population in the U.S. estimated that more than 11,000 of 267,000 employees (4 %) suffered from GERD, contributing an average incremental cost to the employer of $3,355 per employee during a 3-year observation period-approximately 65 % related to prescription drugs. At the same time, it is well recognized that some drugs used...