Cell Engineering: Apoptosis
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The suppression of apoptosis by the IGF system is critical for normal cell development, proliferation, differentiation and motility. Aberrations in IGF signalling mechanisms contribute to cell transformation, tumour progression and metastasis. Many questions remain to be answered as to how exactly the IGF system mediates its effects both in normal and tumour cells and how the IGF-1R interacting proteins and downstream signalling cascades are regulated...
Format:Paperback
Language:English
ISBN:9048166152
ISBN13:9789048166152
Release Date:November 2010
Publisher:Springer
Length:334 Pages
Weight:1.07 lbs.
Dimensions:0.7" x 6.1" x 9.2"
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