This thorough guide is a must-read for cancer patients and their families seeking treatment options. This description may be from another edition of this product.
When a tumor suppressor gene mutates, its ability to prevent uncontrolled growth is turned off.
Published by Thriftbooks.com User , 16 years ago
1. Mutations can be be fixed by enzymes before they cause trouble. There are many enzymes that repair damage DNA in a cell. Some enzymes remove damaged pieces of DNA and fill in the gap with the proper bases, using the opposite strand of DNA as a guide. Other repair enzymes scan the chromosomes for mismatched bases. When a mismatch is discovered, the enzymes remove the wrong base, and replace it with the correct one. 2. Cancer cells replication patterns is controlled by the cyclins. Mitosis has S, G2, M, G1 stages and movement between the stages are controlled by cyclin-dependant Kinases. A cell's progress through the cell cycle is controlled by a group of proteins known as cyclins. For example, cyclin D1 increases as a cell prepares to enter the S stage of mitosis. Only when the right cyclins are at the right level in a cell will it enter the next stage of mitosis. In some cancers cells, it appears that some of the cell cycle genes, both cyclins and th cyclin-dependent kinases, have been mutated. D1 mutations can be found in some cancer cells. Cycline E protein in higher in breast cancer cells. Cycline E may also increase as breast cancers become more aggressive. These changes stimulate the cell to perpetually divide. 3. The mitosis checkpoints fail in cancer cells. The cell continues to divide with gene defects. The checkpoints may allow a cell to resume progress through the cycle even though the damaged remains unrepaired; the cell seems to become accustomed to the damage and sees it as normal. Some scientist think that the checkpoints themselves may have mutated. 4. In normal cells, the cyclins do not act on their own; they are controlled by growth factors, hormones and other growth-stimulating proteins. These proteins are usually manufactured by one type of cell and sent to a different type of cell. They attach to receptors on the cell and send signals inside which, ultimately, control the cyclins and stimulate cell division. 5. When growth factors or other cell stimulants send signals inside the cells, internal molecules must transmit those signals. One of the more commonly mutated oncognese in tumors is call Ras. The Ras protein is part of the signaling pathway which usually leads to cell growth. In some tumors, drugs which can suppress Ras can block the growth of cancer. 6. When a tumor suppressor gene mutates, its ability to prevent uncontrolled growth is turned off. For most tumor suppressors, both tumor suppressor geens in a cell must be damaged in order to promote cancer. Tumor suppressor gene and associated cancers: p53 (Sarcomas, breast cancer), RB (Retinoblastoma), APC (Colon Cancer), DCP4 (Cancer of the pancreas), PTCH (Basal cell carcinoma, skin cancer), BRCA1 & BRCA2 (breast cancer). Cell with mutated genes with an intact p53 can not be repaired, p53 turns on a set of proteins which kill the cell. The process of cell sucide is called apoptosis. 7. As many as 80% of women who inherit mutations in BRCA1 and BRCA2 wil
The First Professional Book On Alternative Cancer Therapy
Published by Thriftbooks.com User , 17 years ago
5-Stars. I don't own this book, but I borrowed it and read it three times, and took notes. I am a mechanical engineer who started studying Alternative Medicine 11 years ago. This book will impress all readers who have the following charactersitics; A logical mind, some basic science background, and a "show me the proof" philosophy. Dr. Ralph Moss's book supplies all the Cancer fighting natural medicines/techniques, with exact, honest proof on its success in humans and animal subjects. I consider this book, although slightly old (1992), the first book to read on natural cancer therapy, for all interested readers.
Excellent info for Cancer
Published by Thriftbooks.com User , 17 years ago
This is the premier book for people looking for solutions. Helped me make mine.
A Practical Handbook to Cancer Therapy
Published by Thriftbooks.com User , 24 years ago
Dr. Moss has put together an excellent resource for people looking into non-toxic cancer treatments. Ralph was thrust into the alternative medicine scene when he brought positive laetrile studies to the public's attention in the1970s when people were saying there was no evidence of laetrile's efficacy. Since then he has been an important voice of reason in the fight for alternatives.This book is a well-researched sourcebook for new and innovative cancer treatments. The book is divided into various sections. The first is "Vitamins," where Moss provides research on vitamins, such as Vitamin D, on cancer research. Moss details studies that have been conducted with vitamins. Other sections include, "Minerals" such as Calcium, "Herbs" such as Aloe, "Diets" such as Gerson, and "Less Toxic Resources" such as Amygdalin and Hydrazine Sulfate. In total he lists over 100 therapies. At the end of each section there are resources for each therapy. For instance, he gives addresses of clinics using the methods.Parts of this book are also devoted to cancer prevention studies. He also will tell when studies show that a substance can, for instance, enhance chemotherapy's effectiveness, or relieve side effects of radiation. This is helpful for people who are not willing to rely totally on alternatives, but who want some of their benefits. This book is useful to anyone researching cancer treatments, cancer preventions, or else just wanting the straight facts on alternative therapies. No major orthodox cancer group approves of most of the therapies Moss discusses. Moss is not a Medical Doctor, but a researcher, so his presentation should not be taken directly as a prescription or a do-it-yourself treatment. However, for a new angle on cancer, and for information on effective therapies, this book is one of the best available.
Consider the Alternative
Published by Thriftbooks.com User , 24 years ago
In his preface, Ralph Moss tells us that "...the hub of the cancer establishment is a highly profitable drug development system, led by chemical, pharmaceutical and biotechnology companies." I have seen this claim corroborated by reputable medical people such as Dr. Samuel Epstein in *The Politics of Cancer* and in Dr. John Robbins' *Reclaiming Our Health.*Moss points out that the major components of the cancer establishment are the National Cancer Institute (NCI), the American Cancer Society (ACS), grantees at major universities, the leading pharmaceutical houses, and the FDA (Federal Drug Administration) "...which regulates the marketplace on behalf of the very industries it is supposed to oversee." Non-toxic cures, on the other hand, are called "questionable, unproven and unscientific" (i.e. unprofitable to the Cancer Industry). Only orthodox cancer treatments - surgery, radiation and chemotherapy -(cutting, burning and poisoning) are "scientific" and presumably not to be questioned. But there is hope. With the formation of the Office of Alernative Medicine (OAM) in 1992, there are now centers of alternative medicine at the medical schools of Harvard, Stanford and Columbia, and a special center to study such treatment has been established at the University of Texas.As yet, I don't have cancer myself, but I have watched beloved family members and friends go brankrupt and die after undergoing these toxic treatments without ever having had the knowledge to seek alternative cures. That is why this book, in my opinion, is such a valuable resource. Moss includes information on cancer prevention as well as alternative treatments with well-documented proof that they have worked for thousands of people all over the world. After each section, the author provides references and resources.Since cancer has increased to epidemic proportions in the industrialized nations, I believe everyone would benefit from owning and reading this [email protected]
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