The role of bacteria including atypical germs in acute exacerbation of chronic obstructive pulmonary disease (COPD) in Tunisia has been variously appreciated. This is a descriptive and analytical study including patients with a mean age of more than 68.3 years hospitalized for COPD. Of the 240 patients included, 175 sputum cultures (73%) were considered significant, 29 cultures were positive (16.5%) and 31 germs were isolated, the most frequent being...