Science never solves apr oblem without creating ten more Geor ge Bernard Shaw How prophetic the above words prove to be when applied to the advances of 20th century medicine. Prior to Banting and Best, chnicians were unaware of the ravages of diabetes, patients simply wasted away and died. Following the purifica- tion of insulin, clinicians now had to deal with diabetic retinopathy, diabetic neph- ropathy and all the other complications of long-term...