""A Comedy of Conscience"" is a satirical novel written by S. Weir Mitchell. It was first published in 1912 and is set in Philadelphia during the early 20th century. The story revolves around the character of John Knox, a wealthy businessman who is known for his ruthless business practices.Knox is suddenly stricken with a mysterious illness that leaves him unable to move or speak. He is confined to his bed and is attended to by his faithful nurse,...