A Change of Heart: How the People of Framingham, Massachusetts, Helped Unravel the Mysteries of Cardiovascular Disease

What my cardiologist ordered to appreciate how one can best care for himself to live a longer life. Easy and very very interesting read. Great history pertaining to heart disease and it causes. May knock some sense into those with a foolish lifestyle.

In a well-narrated, affectionate account of the Framingham study, its current director and a medical journalist, present the study's origins, crises, and ambitious agenda. The book starts off on a fairly dramatic note with a fast-paced account of FDR's final days, which sets the background of the rest of the book. Then, in crisp chapters, the authors present various aspects of the early stages of the study. The chapters dealing with the impact of cholestrol on heart diseases and that of blood pressure on cardiac health are perhaps the best written. The book is a little marred by the sudden shift in the narration style in the last few chapters where the author (probably refering to the lead author alone) use first person account for narration, rather than the third person reporting employed for the earlier chapters. The strong sections of the book will make a reader wish that the authors had explored a bit more in detail about where the future would lead in these trials. The book captures the lead "actors" of the study, since its inception, the loyalty and enthusiasm of the volunteers very inspiringly. One can also see how developments in technology, and analytical methods changed the direction of the study making for a very interesting read. A must read!

Americans everywhere owe a huge debt of gratitude to the citizens of Framingham, Massachusetts who for more than 50 years have voluntarily participated in the groundbreaking Framingham Heart Study. When the study was conceived back in 1948 very little was known about cardiovascular disease. "A Change of Heart" examines the history of the Framingham Heart Study, its methodology and most importantly introduces the reader to some of those who were directly involved in the program both as administrators and as participants. It is a story worth telling. Back in 1948, the average American ate red meat nearly every day. Medical science was not yet aware that high blood pressure was a dangerous contributor to heart attack and stroke. No one thought much about their cholesterol levels, and smoking was far more predominant in the adult populuation than it is today. Middle aged men were dropping like flies and no one understood why. The federal government decided that is was time to conduct a study to look for the root causes of heart disease. Framingham Mass. seemed to be the perfect place for the study and so the government dispatched a physician named Gilkin Meadors and nurse Nell McKeever to Framingham to set up a 20 year study. Meadors and McKeevor enlisted the efforts of a number of community leaders to sell the program to the townspeople. Soon more than 5000 residents had signed up. The requirements were quite simple really. Each participant agreed to submit to a rigorous physical examination every two years and to answer a detailed questionaire about their eating, smoking and exercise habits. Most folks understood that the chief beneficiaries of this study would not be themselves but future generations of Americans. Another unselfish gesture from "The Greatest Generation". Well, the program has been extended a number of times and here we are more than 50 years later and the Framingham Heart Study has proven to be worth its weight in gold. Americans have taken to heart much of what has been learned so far. But as you will learn in "A Change of Heart" there is still considerable room for improvement and so much more to be discovered. Hats off to the people of Framingham for their commitment to this study and to authors Daniel Levy M.D. (the current director of the program)and Susan Brink for a most interesting and informative book. Recommended!

A wonderfully told story about the trials and tribulations of the Famingham Heart Study, it's dedicated and unyielding supporters who helped to bring it to fruition, its heart felt gratitude to the people of Framingham for their enthusiastic involvement making this study possible, and of course its enormous contribution to the understanding and causes of cardiovascular disease which is now moving on to new dimensions and still yet unexplored areas of research.