- Memoir on the Megatherium, or Giant Ground-sloth of America
- Paleontology or a Systematic Summary of Extinct Animals and Their Geological Relations (History of Paleontology)
- Lectures on the Comparative Anatomy and Physiology of the Invertebrate Animals: Delivered at the Royal College of Surgeons; Volume 2d ed.
- Chaucer's Italy
- Report of a Geological Reconnoissance of Indiana: Made During the Years 1859, Under the Direction of the Late David Dale Owen, M. D., State Geologist (Classic Reprint)